Cognitive tasks
Discuss memory, attention, and processing demands in everyday work or study.
Traumatic brain injury & concussion research & care · Scottsdale & Glendale, AZ
Persistent symptoms after concussion can affect thinking, sleep, and the ability to return to familiar routines.
RX-O2 offers a physician-led conversation about the evidence, your diagnosis, and the role of hyperbaric oxygen therapy in your broader care plan. Our Scottsdale and Glendale teams serve patients across the Phoenix area.
Recent research reports encouraging cognitive and sleep findings in selected people with traumatic brain injury. A consultation can connect the evidence to your symptoms and rehabilitation goals. Explore the evidence below.
Physician-led care in Scottsdale and Glendale, serving the Phoenix area.

The starting point
TBI research includes different injury severities and stages of recovery. Much of the recent controlled HBOT evidence concerns persistent symptoms after mild TBI, which may not apply to severe injuries.
Headache, mood, sleep, vestibular symptoms, and cognitive changes can overlap. A coordinated assessment helps identify treatable contributors and avoids attributing every symptom to a single mechanism.
The clinical context matters. Keep your neurologic and rehabilitation care involved. Research does not establish a guaranteed recovery, and trial results differ depending on the comparison group and outcome.
Connect the research to your goals
Discuss memory, attention, and processing demands in everyday work or study.
Track sleep and symptoms with agreed measures that can show meaningful change.
Set realistic participation goals with your rehabilitation or concussion team.
Your goals help shape the conversation and provide a useful way to follow progress if treatment is prescribed.
Explore the evidence
Explore the findings behind the conversation. These selected publications highlight reported benefits, the patients studied, and the questions researchers are still working to answer.
Literature checked
October 20, 2026
2026 · Systematic review and meta-analysis
Publication indexed in PubMed. 2026.
Read the publicationA meta-analysis of eight randomized trials involving 570 participants reported small pooled benefits in cognition, with favorable findings in memory, executive processing, and sleep measures.
How to interpret it: Most evidence concerned mild TBI. Several broader functional, emotional, and symptom outcomes did not show significant benefit, and results should not be generalized to every brain injury.
2013 · Randomized crossover study
Boussi-Gross R, et al. PloS one. 11/15/2013.
Read the publicationA randomized crossover study of 56 people with persistent symptoms one to five years after mild TBI reported improvements in cognitive performance and quality of life after HBOT.
How to interpret it: There was no sham chamber control. The study supports further investigation but cannot fully separate treatment effects from other influences.
2015 · Randomized sham-controlled trial
Publication indexed in PubMed. 2015.
Read the publicationIn a trial of 72 service members, both HBOT and a sham chamber group improved compared with usual care alone. HBOT did not outperform the sham exposure.
How to interpret it: The findings show why suitable comparison groups matter. Positive results across the literature should be discussed alongside this unresolved uncertainty.
The cognitive and sleep findings offer a promising basis for further study and a personalized conversation. Some controlled trials have found no added benefit over sham exposure, so ongoing research remains essential. RX-O2 can help you explore the evidence while keeping your broader recovery plan connected.
Plan with your care team
Bring injury dates, neurologic assessments, imaging when relevant, rehabilitation history, medications, and the symptoms most affecting daily life.
Review the evidence with your treating specialist and hyperbaric clinician. Identify specific outcomes to follow, the alternatives, and the reasons HBOT may or may not be appropriate.
If treatment is prescribed, discuss the schedule, travel, costs, safety screening, and how progress will be reviewed. A published study schedule does not determine an individual prescription.
Your consultation is an opportunity to ask about expected benefits, treatment experience, scheduling, costs, and follow-up. We review suitability with you and coordinate with your treating clinicians when appropriate.
The RX-O2 difference
Medical Director Marvin A. Borsand, DO, FACOS, FACCS, HCC, leads clinical oversight. A licensed medical provider reviews suitability and prescribes treatment when appropriate.
Our clinics use FDA-cleared hard-shell chambers. You breathe 100% medical oxygen through a mask or hood while the chamber is pressurized with air.
NHSA-certified hyperbaric technicians explain the visit and monitor treatment. Tell us about ear pressure, positioning, mobility, or confinement concerns before you arrive.
Before your visit
Some studies report cognitive or symptom improvements, while other controlled trials have not confirmed an added benefit. Your clinical history and goals should guide a careful discussion.
Not automatically. Injury severity, timing, and the outcomes being measured can differ substantially.
No. Continue the care recommended by your treating team and coordinate any additional treatment with them.
RX-O2 has clinics in Scottsdale and Glendale. Bring your records or ask your provider to send a referral so that the team can review your circumstances and explain whether an outpatient consultation is appropriate.
Local care, two Valley locations
Looking for a hyperbaric consultation near Phoenix? RX-O2 offers two locations for patients across the Valley. Call the clinic closest to you for appointment availability and help planning repeat visits.
An East Valley option for patients in Scottsdale, Paradise Valley, Fountain Hills, and nearby communities.
A West Valley option for patients in Glendale, Peoria, Phoenix, and nearby communities.
You do not have to interpret the research alone. Meet with our Scottsdale or Glendale team to discuss your goals, ask questions, and explore whether HBOT is right for you.
Browse the complete HBOT research library · Learn how HBOT works
Selected research checked October 20, 2026. Evidence continues to evolve. This educational overview supports a conversation with your treating clinician; individual results vary.
Read HBOT safety and treatment FAQs. Discuss treatment risks, medicines, implants, and relevant medical history with your clinician. Equipment clearance does not establish effectiveness for every condition.