You breathe medical oxygen
Room air contains about 21% oxygen. During HBOT, you breathe prescribed medical-grade oxygen. At RX-O2, our chambers are pressurized with air while oxygen is delivered through your breathing equipment.
Understanding HBOT · RX-O2 Hyperbaric Clinics
More oxygen. More support for healing.
Hyperbaric oxygen therapy, or HBOT, is a medical treatment that combines breathing medical-grade oxygen with increased pressure inside a chamber. Together, they increase the oxygen dissolved in your blood's plasma, helping deliver oxygen to tissues that need it.
At RX-O2 in Scottsdale and Glendale, we help you understand how this therapy may fit your goals, your condition, and your existing care plan.
Oxygen + pressure
Oxygen is essential to cellular energy, tissue repair, and many immune functions. HBOT creates a controlled environment that allows more oxygen to dissolve into the liquid part of your blood.
Room air contains about 21% oxygen. During HBOT, you breathe prescribed medical-grade oxygen. At RX-O2, our chambers are pressurized with air while oxygen is delivered through your breathing equipment.
Increasing oxygen's partial pressure allows more of it to dissolve in plasma. This principle, called Henry's law, is a foundation of hyperbaric medicine.
The higher oxygen level in the blood strengthens the gradient that moves oxygen into tissue. This can support areas where injury, swelling, or damaged small blood vessels have limited oxygen delivery.
Why can HBOT help when a pulse oximeter already reads normally? A pulse oximeter estimates oxygen saturation on hemoglobin in red blood cells. HBOT also increases oxygen dissolved directly in plasma. A normal fingertip reading does not measure all aspects of tissue oxygen delivery.
The biology behind the treatment
The NHSA training curriculum explores several ways oxygen under pressure affects the body. These mechanisms help explain HBOT's role in selected medical conditions.
Higher dissolved oxygen levels can improve oxygen availability in tissues affected by reduced blood supply or injury.
HBOT can reduce edema in certain injuries while increasing oxygen availability. It also influences inflammatory signaling and the behavior of immune cells.
Oxygen supports collagen production and wound repair. Repeated treatments can stimulate signals involved in new small blood vessel formation, known as angiogenesis.
In selected infections, HBOT supports oxygen-dependent immune defenses and can inhibit some bacteria and their toxins. It is used alongside the appropriate antibiotics, surgery, or wound care.
The benefit, treatment schedule, and strength of evidence depend on the condition being treated. A biological mechanism does not establish the same outcome for every patient or diagnosis.
Examples of conditions with recognized roles for HBOT include:
Research also explores HBOT's effects on cellular signaling, stem and progenitor cells, and neurologic recovery. Some applications are off-label or remain under investigation, with evidence that varies by diagnosis.
A consultation gives you a chance to discuss the evidence for your situation, what a treatment plan would involve, and how progress could be evaluated.
Talk with a hyperbaric specialist
Get familiar with the setting
Both RX-O2 locations offer FDA-cleared monoplace and multiplace chambers. Our team helps you choose the setting that fits your treatment and practical needs.
Designed for one person, with room to sit upright or recline. Your team prepares your breathing equipment and monitors your session from outside the chamber.
Larger chambers designed to accommodate more than one person. They offer options for shared treatments, parent-and-child care, and mobility needs when arranged and medically cleared.
If enclosed spaces or getting into the chamber concern you, tell us. We can show you the available options and discuss the help you may need before booking treatment.
A brief history of hyperbaric medicine
The idea of using pressure in medicine came before oxygen was identified in the 1770s. Modern HBOT grew from that early curiosity, the needs of divers and tunnel workers, and research into how oxygen reaches living tissue.
Blood carries oxygen on red blood cells and dissolved in plasma. Research by Dr. Ite Boerema and colleagues helped demonstrate how much the plasma pathway could contribute under increased oxygen pressure.
That principle remains central to understanding modern hyperbaric treatment.
View the 1960 publication recordHenshaw's “domicilium” explored the use of changing air pressure for health. It was an early ancestor of the medical pressure chamber, before oxygen-based treatment was possible.
Andrew Smith documented “caisson disease” among Brooklyn Bridge workers. Understanding the effects of compressed air and pressure changes helped drive the development of recompression care.
Orville Cunningham's large steel sphere in Cleveland housed a compressed-air hospital. The striking structure represents an ambitious early chapter in pressure therapy, before today's oxygen protocols and clinical standards.
Boerema's animal experiments explored oxygen delivery under pressure when very little hemoglobin was available. The work, reported in “Life without blood,” helped establish a foundation for modern hyperbaric physiology.
The Undersea Medical Society was established. It later became the Undersea and Hyperbaric Medical Society, bringing diving and clinical hyperbaric medicine together.
HBOT has recognized roles in wound care, selected infections, radiation injury, and diving medicine. Research continues into other applications, with patient selection and evidence guiding clinical decisions.
Historical overview adapted from the National Hyperbaric Safety Association training materials supplied by RX-O2. Early compressed-air treatments were predecessors of modern HBOT; historical use alone does not establish effectiveness.
Medical care starts before pressurization
Education is part of our clinic culture
RX-O2 serves as an NHSA teaching facility, and our facilities have received NHSA Facility Certification of Compliance. The training curriculum connects oxygen physiology with chamber operations, patient preparation, and emergency procedures.
Our Medical Director, Marvin A. Borsand, DO, FACOS, FACCS, guides medical care. Our safety and technical team supports the preparation and operation of each session.
Meet our medical and safety team →What does HBOT feel like?
Many patients use their session to rest or enjoy approved reading material. The most noticeable sensation is often ear fullness as the pressure changes, similar to what you may feel on an airplane.
Your team teaches you how to equalize your ears. If you feel pain or discomfort, tell the staff immediately so they can respond and adjust the process as needed.
Take a closer look at your first HBOT visit →Explore the experiences patients share across our Scottsdale and Glendale clinics.
Find each clinic's patient reviews →
Common questions
Bring your questions to our team. You do not need a background in hyperbaric medicine to take the first step.
Schedule a consultationHBOT combines medical oxygen with an increase in pressure around your whole body. Breathing supplemental oxygen at normal room pressure is a different treatment. The chamber environment changes how much oxygen can dissolve in your blood.
ATA means atmospheres absolute, a measure of total pressure. Normal air pressure at sea level is about 1 ATA. Your provider chooses the treatment pressure and oxygen exposure as part of your prescription.
No. Chamber design, permitted operating pressure, oxygen delivery, clinical oversight, and the prescribed protocol all matter. Both RX-O2 locations use FDA-cleared monoplace and multiplace chambers. Our team can explain the equipment and treatment options available to you.
That depends on your condition, goals, and response. Many treatment plans involve a series of sessions with progress reviewed along the way. Your consultation is the place to discuss a reasonable starting plan and how your provider will evaluate results.
Possible effects include ear or sinus discomfort, pressure-related injury, and temporary vision changes. Less common complications include oxygen toxicity. Screening, prescribed oxygen exposure, and trained monitoring help manage risk. Your provider will review your individual health history before treatment.
FDA clearance relates to a medical device and its intended uses. It does not mean every condition discussed in HBOT research has an FDA-cleared indication or proven benefit. Your provider can explain the evidence and whether a proposed use is off-label.
You do not need all the answers before contacting us. Bring your questions, your current care plan, and what you hope to understand. A consultation can help you weigh potential benefits, uncertainty, practical needs, and costs before making a treatment decision.
Learn more: This overview draws on NHSA training materials, hyperbaric medical references, and the clinic information provided by RX-O2.