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Cerebral palsy · Scottsdale & Glendale

Hyperbaric oxygen therapy for cerebral palsy

Explore the possibilities for movement, communication, and everyday life. Some studies of HBOT in cerebral palsy have reported encouraging gains in motor skills, gait, and language measures.1, 2, 3

At RX-O2, we welcome your questions and the goals that matter to your family. Meet with our hyperbaric team to review the research, discuss suitability, and explore how a plan could fit alongside existing care.

HBOT for cerebral palsy is an off-label use. Research is conflicting: several controlled trials found no added benefit over comparison treatments. It is not an established cure or a replacement for rehabilitation.6, 7, 8

Members of the RX-O2 hyperbaric team standing together at the clinic
Your questions. Your goals. Our team.A welcoming place to explore your next step.
Members of the RX-O2 team.
FDA-cleared chambersHard-shell hyperbaric systems
100% medical oxygenBreathed through a dedicated mask or hood
Physician-led careIndividual medical evaluation
NHSA-certified techniciansAttentive support during treatment

A family’s experience at RX-O2

Donna & James: changes that mattered in everyday life

For Donna, the changes she saw in her son James after treatment at RX-O2 were life-changing.

Donna reports improvements in James’s speech patterns and gait, an ability to walk for longer, and a dramatic improvement in his quality of life.

She is deeply thankful to the RX-O2 team and describes the experience as giving James a new life.

Donna, James’s mother
Family account, summarized by RX-O2.

Changes Donna reported

  • Improved speech patterns
  • Improved gait
  • Walking for longer
  • Better quality of life

Every family brings its own priorities. We are here to listen to yours.

Talk with a hyperbaric specialist

This is one family’s reported experience. It does not establish that HBOT caused every change or predict another person’s results. Research has not established a typical improvement in walking or speech from HBOT for cerebral palsy.

Start with what matters to you

Potential benefits worth understanding

A meaningful goal may be a more comfortable movement, easier communication, or greater participation in daily life. These areas offer useful starting points for a consultation.

01 / Gait & balance

Exploring steadier movement

A small randomized trial reported better walking and balance measurements when HBOT was added to physical therapy. It involved children who could already walk; it does not show that HBOT will enable a person who cannot walk to do so.1

02 / Motor skills

Building on rehabilitation goals

An observational study found larger gains in gross motor scores in children receiving hyperbaric treatment alongside intensive rehabilitation. Its nonrandomized design leaves uncertainty about how much benefit came from the chamber treatment.2

03 / Communication

Making communication part of the plan

A meta-analysis reported favorable language-expression and comprehension results, but rated the evidence very low certainty. Bring your speech-therapy goals, including communication aids, so the discussion reflects your family’s needs.3

04 / Movement comfort

Looking at muscle tone and hand function

An early pilot study reported improvements in selected hand-function and muscle-tone assessments. These findings are exploratory and provide questions to discuss alongside established spasticity management.4

You do not need all the answers before contacting us. Bring your questions, your current care plan, and what you hope to understand. A consultation can help you weigh potential benefits, uncertainty, practical needs, and costs before making a treatment decision.

Understanding the approach

Why oxygen is being studied in cerebral palsy

Cerebral palsy describes a group of conditions affecting movement and posture after differences in, or injury to, the developing brain. Its effects and support needs vary widely.10

HBOT increases the oxygen dissolved in blood during treatment. Researchers are exploring whether oxygen-related changes in brain metabolism, circulation, and signaling can support function in selected neurological conditions.

These mechanisms help explain the research interest. They do not establish that every person with cerebral palsy has ongoing oxygen deprivation or that HBOT can reverse the original brain injury.

At your consultation, the focus is practical: what has been studied, how closely the participants resemble your situation, and whether the potential value justifies treatment for you. Physical, occupational, and speech therapies remain central to an individual care plan.

Explore the published research

Encouraging findings, clearly explained

The research includes positive clinical reports, newer analyses, and trials with different conclusions. Read what improved, who was studied, and what each result can tell us.

Literature checked
September 12, 2026

2023 · Randomized clinical trial

Gait and balance improvements alongside physical therapy

39 children with spastic hemiplegic cerebral palsy · ages 5–10

Children receiving HBOT plus physical therapy had more favorable gait and balance measurements than those receiving physical therapy alone, including at follow-up. This offers an encouraging finding for families interested in mobility.

The study was small, had no sham-chamber group, and enrolled children in GMFCS levels I–II. Its results do not establish benefit for all mobility levels or for adults.

Read the gait and balance trial

2024 · Reanalysis of published studies

Revisiting motor progress over time

44 studies across therapies · four involved hyperbaric treatment

Researchers compared observed motor-score gains with the changes expected from development. Their analysis found encouraging progress ratios in the hyperbaric groups and proposed a different way to interpret earlier research.

This was a comparison across existing studies, not a new randomized trial. Oxygen and pressurized-air groups had similar ratios. Differences in participants, study quality, and accompanying therapies prevent a conclusion that HBOT outperforms standard rehabilitation.

Read the motor-progression analysis

2022 issue · Systematic review & meta-analysis

Positive motor and language signals

25 studies · 2,146 participants overall · published online in 2021

The pooled analysis favored HBOT on selected motor, developmental, and language measures. Different outcomes used different subsets of the included participants.

The authors rated the certainty of evidence very low for all assessed outcomes. The findings are promising signals, not a reliable estimate of the improvement an individual can expect.

Read the motor and language review

2014 · Controlled observational study

Greater motor gains with combined care

150 children · intensive rehabilitation with or without hyperbaric treatment

All groups improved. Children in the three hyperbaric groups showed larger gains in gross motor function than the rehabilitation-only group, with follow-up over eight months.

Assignment was not randomized, and one chamber group used pressurized air. There was no significant difference among the chamber groups, so the findings do not isolate an oxygen-specific benefit.

Read the combined-rehabilitation study

How do these findings fit with controlled trials?

A 111-child trial found similar improvements with HBOT and slightly pressurized air. A later blinded trial found no gross-motor improvement and no additional functional benefit from HBOT. A 2022 systematic review concluded that the higher-quality evidence did not support HBOT for improving motor or cognitive function in children with cerebral palsy.6, 7, 8

This is why we discuss possible benefits alongside the uncertainty, preserve established therapies, and make the consultation about an informed choice for your family.

1999 pilot: selected motor, hand-function, and muscle-tone changes

In 25 children with spastic diplegic cerebral palsy, researchers reported improvements in selected gross-motor categories, hand tasks, and muscle groups after HBOT. Without a comparison group, natural development, practice effects, and other care could not be separated from treatment effects. Read the pilot study.

2025 caregiver study: a reminder that support at home matters

A study in a pediatric HBOT setting reported improvements after a video-assisted caregiver teaching program. The intervention being evaluated was caregiver education. It supports attention to family participation but does not isolate the effectiveness of HBOT. Read the caregiver-education study.

2001 multicentre trial: why the comparison group matters

The 111-child trial found gains in both groups without a significant advantage for HBOT. Researchers continue to debate the biological activity of pressurized-air controls. That debate does not establish that HBOT improves outcomes compared with usual care. Read the multicentre trial.

2012 blinded trial and the 2022 evidence review

The later trial did not find an added motor or functional advantage for HBOT. The 2022 review assessed study quality and safety and advised against its use for the motor and cognitive outcomes studied. These findings deserve consideration alongside the favorable reports. Read the blinded trial and the systematic review.

Find newer cerebral palsy and HBOT research on PubMed. Results are sorted by publication date; newly listed papers have not necessarily been assessed for this page.

A consultation built around the person

Bring your care plan and the changes you hope to see

For one person, a priority may be walking endurance. For another, it may be transfers, hand use, or communicating a choice. We want to understand those priorities before discussing treatment.

A licensed medical provider reviews medical history, potential benefits, risks, and treatment suitability. Your rehabilitation and neurology teams can help identify meaningful goals and track progress if HBOT is pursued.

  • Diagnosis and relevant medical notes
  • Current physical, occupational, and speech therapies
  • Medicines and seizure history
  • Mobility, transfer, and positioning needs
  • Ear, breathing, and feeding concerns
  • Communication preferences and support needs

Tell us about an implanted pump or other medical device before your visit. Compatibility must be reviewed for the proposed chamber conditions. Do not change prescribed medicines or stop rehabilitation in preparation for HBOT.

Progress should be meaningful to you. Agree on a small number of goals and record a starting point with the treating team. Follow-up should consider function, comfort, treatment burden, and whether continuing makes sense.

The RX-O2 difference

Your facility matters. So does your team.

From your first questions to each treatment visit, our Scottsdale and Glendale clinics focus on medical oversight, patient education, and attentive care.

A blood-pressure check beside open hyperbaric chambers at RX-O2 Scottsdale
Preparing for treatment at RX-O2 Scottsdale.

Care led by a physician

Medical Director Marvin A. Borsand, DO, FACOS, FACCS, HCC, leads clinical oversight. A licensed medical provider evaluates suitability and prescribes treatment when appropriate.

FDA-cleared hard-shell chambers

Our facilities use prescription-level hyperbaric systems, with chamber selection and treatment settings matched to your prescribed plan.

100% medical-grade oxygen

You breathe oxygen through a dedicated mask or hood while the chamber is pressurized with air. Your technicians monitor you throughout treatment.

NHSA-certified hyperbaric technicians

Our technicians are certified through the National Hyperbaric Safety Association and trained in chamber operations, patient monitoring, and emergency procedures.

Meet the RX-O2 team

Feel more prepared for your first visit

A supportive start for patients and caregivers

  1. Plan for comfort

    Discuss seating, transfers, mask or hood tolerance, and communication before arrival. Ask which chamber arrangement fits the individual’s needs.

  2. Understand the experience

    Our team explains pressure changes, ear equalization, and how to communicate discomfort. Pediatric visits require planning for a caregiver; accompanying caregivers also need clearance.

  3. Review the full plan

    If treatment is appropriate, discuss visits, reassessment, costs, and coordination with existing therapies before choosing a package.

Local care, two Valley locations

Explore HBOT in Scottsdale or Glendale

Looking for a hyperbaric consultation near Phoenix? RX-O2 offers two locations for patients across the Valley. Call the clinic closest to you for appointment availability and help planning repeat visits.

Your questions are welcome

Cerebral palsy and HBOT FAQs

A consultation gives you time to explore the possibilities, ask about the evidence, and understand the practical details.

What benefits have been reported with HBOT for cerebral palsy?

Some studies report changes in gait, balance, selected motor skills, and language measures. Results differ between studies, and several controlled trials found no added benefit. A consultation can help you understand whether the participants and goals studied resemble your situation. Explore the research.

Could HBOT help with walking or speech?

These are reasonable goals to discuss. The gait trial involved children who could already walk, and pooled language findings were rated very low certainty. Research does not establish that HBOT enables independent walking or speech for a particular person. Keep physical and speech therapy, including communication aids, in the plan.

Will my family see the same changes Donna reported for James?

James’s story reflects one family’s experience. We cannot predict the same changes for someone else or attribute every change to HBOT. There is no established typical improvement to promise. Your consultation focuses on the individual’s medical history, goals, suitability, and a plan for reassessment.

Is cerebral palsy an FDA-approved indication for HBOT?

No. HBOT for cerebral palsy is an off-label use. RX-O2 uses FDA-cleared chambers, but equipment clearance does not establish effectiveness or FDA approval for treating cerebral palsy.

Can adults with cerebral palsy schedule a consultation?

Yes. Adults can contact RX-O2 to discuss their goals and medical suitability. Most published CP research described here involves children, so it cannot establish benefits for adults. The evaluating provider will discuss that limitation and how it affects the decision.

Should physical, occupational, or speech therapy continue?

Yes, according to the treating team’s plan. Rehabilitation and support for communication, mobility, and participation remain central. HBOT should not displace established therapies, prescribed medicines, or recommended orthopedic and neurological care.

What are the main safety considerations?

Ear-pressure injury is a particular concern in children. Other risks include temporary vision changes and confinement anxiety; uncommon serious complications include oxygen-induced seizures and lung injury. Tell the provider about seizures, lung disease, ear problems, medicines, and implanted devices. An untreated pneumothorax prevents treatment.8, 12

What if a patient has difficulty clearing their ears or communicating discomfort?

Discuss this before scheduling treatment. The provider and technicians assess whether a safe approach is possible and explain how the patient or caregiver can signal discomfort. Treatment should not continue through pain. Some patients need additional assessment or a different plan.

Can a caregiver accompany a child?

Discuss caregiver arrangements during the consultation. Our chamber options include larger walk-in systems, and accompanying caregivers require medical clearance and safety preparation. Electronics and battery-powered devices are not allowed inside chambers. Ask the team about approved comfort items and communication arrangements.

How many treatments are needed, and what will they cost?

There is no universally established HBOT course for cerebral palsy. The provider discusses suitability, goals, reassessment, and the potential time and financial commitment. Review current pricing and packages after your consultation, and confirm any insurance coverage before purchasing.

Where can we book a cerebral palsy HBOT consultation near Phoenix?

RX-O2 welcomes patients and families at our Scottsdale and Glendale clinics. Call Scottsdale at 480-270-6090, Glendale at 623-930-0887, or schedule online.

Let’s talk about the possibilities for your family.

Bring your questions to RX-O2 in Scottsdale or Glendale. We will help you explore the evidence and take an informed next step.

Sources & further reading

  1. Khalil ME, et al. Long-Term Effect of Hyperbaric Oxygen Therapy on Gait and Functional Balance Skills in Cerebral Palsy Children—A Randomized Clinical Trial. Children. 2023;10(2):394.
  2. Mukherjee A, et al. Intensive rehabilitation combined with HBO2 therapy in children with cerebral palsy: a controlled longitudinal study. Undersea Hyperb Med. 2014;41(2):77–85.
  3. Zhang Y, Wu J, Xiao N, Li B. Hyperbaric Oxygen Therapy Is Beneficial for the Improvement of Clinical Symptoms of Cerebral Palsy: A Systematic Review and Meta-Analysis. Complement Med Res. 2022;29(2):158–171. Published online September 17, 2021.
  4. Montgomery D, et al. Effects of hyperbaric oxygen therapy on children with spastic diplegic cerebral palsy: a pilot project. Undersea Hyperb Med. 1999;26(4):235–242.
  5. Marois P, Letellier G, Marois M, Ballaz L. Using the gross motor function measure evolution ratio to compare different dosage of hyperbaric treatment with conventional therapies in children with cerebral palsy – could it end the controversy? Front Neurol. 2024;15:1347361.
  6. Collet JP, et al. Hyperbaric oxygen for children with cerebral palsy: a randomised multicentre trial. HBO-CP Research Group. Lancet. 2001;357(9256):582–586.
  7. Lacey DJ, Stolfi A, Pilati LE. Effects of hyperbaric oxygen on motor function in children with cerebral palsy. Ann Neurol. 2012;72(5):695–703.
  8. Laureau J, Pons C, Letellier G, Gross R. Hyperbaric oxygen in children with cerebral palsy: A systematic review of effectiveness and safety. PLoS One. 2022;17(10):e0276126.
  9. Abd-Elzaher RAE, et al. Effectiveness of video assisted teaching program for caregivers on gross motor outcome among children with cerebral palsy undergoing hyperbaric oxygen therapy: A quasi-experimental study. Sci Rep. 2025;15.
  10. Centers for Disease Control and Prevention. About Cerebral Palsy.
  11. U.S. Food and Drug Administration. Follow Instructions for Safe Use of Hyperbaric Oxygen Therapy Devices. Letter to Health Care Providers, August 25, 2025.
  12. Heyboer M III, Sharma D, Santiago W, McCulloch N. Hyperbaric Oxygen Therapy: Side Effects Defined and Quantified. Adv Wound Care. 2017;6(6):210–224.

These references include clinical trials, observational reports, reviews, a caregiver-education study, and safety information. Reviews can include trials listed separately; they are not independent replications. Donna and James’s family account is separate from the research evidence.

Literature checked September 12, 2026. New papers require assessment before their findings are added. This page is a selected research overview. Educational information does not replace diagnosis or an individual treatment plan.